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human timp 1 quantkine elisa kit rd systems  (R&D Systems)


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    R&D Systems human timp 1 quantkine elisa kit rd systems
    Human Timp 1 Quantkine Elisa Kit Rd Systems, supplied by R&D Systems, used in various techniques. Bioz Stars score: 95/100, based on 165 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/quantkine+elisa/Human+TIMP-1+Quantikine+ELISA+Kit/pmc12108053__msphere%2E00102-25-s0001-6-0-5
    Average 95 stars, based on 165 article reviews
    human timp 1 quantkine elisa kit rd systems - by Bioz Stars, 2026-10
    95/100 stars

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    Comparison of 5DEX-0509R with the clinical stage agent MBS-8 and its effect on human PBMCs and monocyte-derived M2 macrophages. (A) Antitumor effect and blood cytokine profiles of MBS-8 and 5DEX-0509R. LLC-bearing mice ( n = 6 per group) were intravenously injected once a week with 5DEX-0509R (0.1 mpk) and MBS-8 (100 nmol/mouse). Data show the average tumor size in each of the groups. Data are shown as mean ± SD. Statistical differences were evaluated by the parametric Dunnett test vs vehicle (PBS treatment, * p < 0.05). (B) Cytokine profiles of 5DEX-0509R (0.1 mpk as equivalent dose of DSP-0509) and MBS-8 (100 nmol/mouse). Data are shown as mean ± SD. Statistical differences were evaluated by t -tests. (C, D) CD206 expression and <t>TNFα</t> production from PBMCs (C) and monocyte-derived M2 macrophages (D). Each of the cells (PBMCs and M2 macrophages) was stimulated with 1 μM DSP0509 and 5DEX-0509R, and their supernatants were subjected to TNFα measurement.
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    Comparison of 5DEX-0509R with the clinical stage agent MBS-8 and its effect on human PBMCs and monocyte-derived M2 macrophages. (A) Antitumor effect and blood cytokine profiles of MBS-8 and 5DEX-0509R. LLC-bearing mice ( n = 6 per group) were intravenously injected once a week with 5DEX-0509R (0.1 mpk) and MBS-8 (100 nmol/mouse). Data show the average tumor size in each of the groups. Data are shown as mean ± SD. Statistical differences were evaluated by the parametric Dunnett test vs vehicle (PBS treatment, * p < 0.05). (B) Cytokine profiles of 5DEX-0509R (0.1 mpk as equivalent dose of DSP-0509) and MBS-8 (100 nmol/mouse). Data are shown as mean ± SD. Statistical differences were evaluated by t -tests. (C, D) CD206 expression and TNFα production from PBMCs (C) and monocyte-derived M2 macrophages (D). Each of the cells (PBMCs and M2 macrophages) was stimulated with 1 μM DSP0509 and 5DEX-0509R, and their supernatants were subjected to TNFα measurement.

    Journal: ACS Nano

    Article Title: Targeting Tumor-Associated Macrophages with the Immune-Activating Nanomedicine for Achieving Strong Antitumor Activity with Rapid Clearance from the Body

    doi: 10.1021/acsnano.4c08811

    Figure Lengend Snippet: Comparison of 5DEX-0509R with the clinical stage agent MBS-8 and its effect on human PBMCs and monocyte-derived M2 macrophages. (A) Antitumor effect and blood cytokine profiles of MBS-8 and 5DEX-0509R. LLC-bearing mice ( n = 6 per group) were intravenously injected once a week with 5DEX-0509R (0.1 mpk) and MBS-8 (100 nmol/mouse). Data show the average tumor size in each of the groups. Data are shown as mean ± SD. Statistical differences were evaluated by the parametric Dunnett test vs vehicle (PBS treatment, * p < 0.05). (B) Cytokine profiles of 5DEX-0509R (0.1 mpk as equivalent dose of DSP-0509) and MBS-8 (100 nmol/mouse). Data are shown as mean ± SD. Statistical differences were evaluated by t -tests. (C, D) CD206 expression and TNFα production from PBMCs (C) and monocyte-derived M2 macrophages (D). Each of the cells (PBMCs and M2 macrophages) was stimulated with 1 μM DSP0509 and 5DEX-0509R, and their supernatants were subjected to TNFα measurement.

    Article Snippet: For human cytokine measurement, Quantkine human TNFα ELISA kits (R and D Systems) were used according to the manufacturer’s instructions.

    Techniques: Comparison, Derivative Assay, Injection, Expressing